<em>In vivo</em> Macrophage Imaging Using MR Targeted Contrast Agent for Longitudinal Evaluation of Septic Arthritis

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

In vivo macrophage imaging using MR targeted contrast agent for longitudinal evaluation of septic arthritis.

Macrophages are key-cells in the initiation, the development and the regulation of the inflammatory response to bacterial infection. Macrophages are intensively and increasingly recruited in septic joints from the early phases of infection and the infiltration is supposed to regress once efficient removal of the pathogens is obtained. The ability to identify in vivo macrophage activity in an in...

متن کامل

HER2 Targeted Molecular MR Imaging Using a De Novo Designed Protein Contrast Agent

The application of magnetic resonance imaging (MRI) to non-invasively assess disease biomarkers has been hampered by the lack of desired contrast agents with high relaxivity, targeting capability, and optimized pharmacokinetics. We have developed a novel MR imaging probe targeting to HER2, a biomarker for various cancer types and a drug target for anti-cancer therapies. This multimodal HER20tar...

متن کامل

Recent Advances in PET-MR Hybrid contrast agent

Introduction: All of the Imaging modalities have advantages and disadvantages alone. So if we want to have the best and perfect image, combining these modalities produces something we desired. PET-MR images consist of morphologic and metabolic data. MRI and PET provide high spatial and contrast resolution and high sensitivity and molecular information respectively. Hybrid PET-...

متن کامل

Imaging hypoxia using a nitroimidazole based T1 MR contrast agent

Introduction: Hypoxic regions in tumors are known to affect radiation sensitivity and promote development of metastases [1]. Noninvasive imaging based methods such as MRI are particularly suitable for longitudinal measurements and generation of three-dimensional spatial maps of tumor hypoxia [2]. An MRI method that could differentiate hypoxic versus normoxic tissues without relying on washout m...

متن کامل

Multi-Modality PET-MR Perfluorocarbon Nanoparticle Contrast Agent for Ligand-Targeted Quantitative Imaging

Introduction. The combination of positron emission tomography and magnetic resonance imaging offers a major breakthrough in detecting, characterizing and monitoring disease. This work introduces a novel contrast agent, detected by both modalities, which employs a self-inserting chelator with linker peptide derived from melittin (a host defense peptide in honeybee venom). Based on a lipid-encaps...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Visualized Experiments

سال: 2013

ISSN: 1940-087X

DOI: 10.3791/50296